Robert G. Weiss, M.D.
Professor of Medicine, Division of Cardiology
Professor of Radiology

Director, Donald W. Reynolds
Cardiovascular Clinical Research Center
Director, Project 2

rweiss@jhmi.edu

Dr. Weiss is Professor of Medicine in the Division of Cardiology, Professor of Radiology, and Director of Cardiac MR Spectroscopy.  As Principal Investigator for Project 2 in the Donald W. Reynolds Cardiovascular Clinical Research Center, he is leading efforts to develop new, non-invasive imaging and spectroscopic techniques to identify individuals at greatest risk for sudden cardiac death. 

With a broad spectrum of clinical and basic research interests in cardiovascular medicine and imaging, Dr. Weiss has a strong track record of innovation and leadership at Johns Hopkins University. 

His recent publications include:

1. Naumova AV, Weiss RG, Chacko VP.  Regulation of murine myocardial energy metabolism during adrenergic stress studied by in vivo 31P NMR spectroscopy. Am J Physiol Heart Circ Physiol 2003; 285(5): H1976-9.
2. Bottomley PA, Ouwerkerk R, Lee RF, Weiss RG. Four-angle saturation transfer (FAST) method for measuring creatine kinase reaction rates in vivo. Magn Reson Imaging 2002; 47(5): 850-63.
   
3. Weiss RG, et al. An increase in the myocardial PCr/ATP ratio in GLUT4 null mice. FASEB 2002; 16(6): 613-5.
   
4. Bottomley PA, Weiss RG.  Noninvasive localized MR quantification of creatine kinase metabolites in normal and infracted canine myocardium. Radiology 2001; 219(2): 411-8.
   
5. Weiss RG, Mejia MA, Chacko VP, DiPaula AF, Becker LC, Kass DA, Gerstenblith G,: Preservation of canine myocardial high-energy phosphates during low-flow ischemia with synthetic allosteric modification of hemoglobin-oxygen affinity. The Journal of Clinical Investigation 103:739-746, 1999.
   
6. Bottomley PA and Weiss RG: Creatine depletion in non-viable, infarcted myocardium measured by noninvasive MRS.  The Lancet 351:714-718; 1998.