Gordon F. Tomaselli, M.D.
Chief, Division of Cardiology
Vice-Chair of Research, Department of Medicine
Professor of Medicine, Division of Cardiology
Co-Director, The Donald W. Reynolds
Cardiovascular Clinical Research Center
Director, ICD Registry
gtomasel@jhmi.edu | 
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Dr. Tomaselli is a Professor of Medicine in the Division of Cardiology & Molecular Medicine at the Johns Hopkins University School of Medicine. In this role he attends the clinical electrophysiology laboratory, teaches physiology, pathophysiology, and molecular medicine to first and second year medical students, and has an active basic laboratory research program. Dr. Tomaselli is known for his work on cardiac electrophysiology and arrhythmias, and his laboratory interests include the structure and function of ion channel genes and proteins, and molecular genetic changes in excitability molecules which occur in the human heart failure. Dr. Tomaselli is leading the clinical research efforts within the Donald W. Reynolds Cardiovascular Clinical Research Center as Co-Director. In addition to this role, he serves as the principal investigator on Project 3: Expression Profiling and Proteomic Biomarkers of Sudden Cardiac Death. He is board certified in cardiovascular diseases, and clinical electrophysiology and pacing. He is the President of the Cardiac Electrophysiology Society, a member of the Committee on Scientific Sessions Resource Planning (CSSP) of the American Heart Association and a member of the leadership Committee for the Council on Basic Cardiovascular Sciences of the American Heart Association. He is Chairman of the Basic Sciences subsection of the NASPE – Heart Rhythm Society Program Committee. He serves on the editorial board of Circulation and is an Associate Editor of Circulation Research and is a former permanent member and now on reviewer reserve of the Electrical Signaling, Ion Transport and Arrhythmias [ESTA] Institutional Review Group at the National Institutes of Health, The National Heart Lung & Blood Institute. Selected recent publications include: - Akar FG, Wu RC, Deschenes I, Armoundas AA, Piacentino V, Houser SR, Tomaselli GF. Phenotypic differences in the transient outward K+ current of human and canine ventricular myocytes: insights into the molecular composition of ventricular Ito. Am J Physiol Heart Circ Physiol 2003; October 2, Published Ahead of Print.
- Nasir K, Tandri H, Rutberg J, Tichnell C, Spevak P, Crossan J, Baughman KL, Kasper EK, Tomaselli GF, Berger R, Calkins H. Filtered QRS duration on signal-averaged electrocardiography predicts inducibility of ventricular tachycardia in arrhythmogenic right ventricle dysplasia. Pacing Clin Electrophysiol 2003; 26(10): 1955-60.
- Spragg DD, Leclercq C. Loghmani M. Faris OP, Tunin RS, DiSilvestre D, McVeigh ER, Tomaselli GF, Kass DA. Regional alterations in protein expression in the dyssynchronous failing heart. Circulation 2003; 108(8): 929-32.
- Kondratiev A, Tomaselli GF. Altered gating and local anesthestic block mediated by residues in the I-S6 and II-S6 transmembrane segments of voltage-dependent Na+ channels. Mol Pharmacol 2003; 64(3): 741-52.
- Xiong W, Li RA, Tian Y, Tomaselli GF. Molecular motions of the outer ring of charge of the sodium channel: do they couple to slow inactivation? J Gen Physiol 2003; 122(3): 323-32.
- Tomaselli GF, Donahue JK. Somatic gene transfer and cardiac arrhythmias: problems and prospects. J Cardiovas EP 2003; 14:547-50.
- Deschênes I, Tomaselli GF. Modulation of Kv4.3 current by accessory subunits. FEBS Lett 2002; 528:1-3.
- Deschênes I, DiSilvestre, D. Juang, G. J. Wu, R. C. An, W. F., Tomaselli GF. Regulation of Kv4.3 current by KChIP2 splice variants: a component of native cardiac Ito? Circulation 2002;106:423-9.
- Deschênes I, Neyroud N, DiSilvestre, D. Marbán E, Yue DT, Tomaselli GF. Isoform-specific modulation of voltage-gated Na(+) channels by calmodulin. Circ Res 2002; 90: E49-57.
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