| Dr. Lima has distinguished himself in clinical and scientific scholarships as well as teaching. The majority of his effort has been dedicated to clinical scholarship and program development at Johns Hopkins. Dr. Lima is an outstanding clinician, and a local and national expert in Cardiac MRI and echocardiography. Dr. Lima’s primary contribution to the advancement of science has been his work on the pathophysiology of the left ventricular remodeling after myocardial infarction. Using non-invasive techniques such as Cardiac MRI and echocardiography to evaluate left ventricular function after myocardial infarction. Dr. Lima has become one of the nationally recognized authorities in the field of cardiac post-infarct remodeling. Dr. Lima was one of the first investigators to document the mismatch between myocardial dysfunction and ischemia/infarction after coronary occlusion and it’s response to changes in loading conditions. In addition, Dr. Lima developed a chronic ovine model of myocardial infarction and utilized MRI tissue tagging to characterize myocardial deformation and rigid body motion in the infarcted left ventricle over the course of one year after the ischemic event. Research interests are concentrated on the development and application of imaging and technology to address scientific and clinical problems involving the heart and vascular system. Efforts have been directed to the development of MR contrast techniques to investigate microvascular function in patients experimental animals with myocardial infarction; functional reserve secondary to dobutamine stimulation and myocardial viability assessed by sodium imaging. Cardiac MR and CT program development of techniques to characterize atherosclerosis in humans with cardiovascular or cerebrovascular disease. |